General Instructions:For this (and all) assignments please keep answers concise. Point form answers are acceptable, asis creating tables/diagrams to answer questions more concisely. Marks will be deducted foroverly lengthy answers.If you are asked to diagram a process or graph data, the figure should be produced by you (eitherby hand or digitally and inserted in your document). Copying and pasting of images from the textor other sources will result in a grade of 0 for the related question.References:Each question can be answered using your text, lecture notes and your knowledge andunderstanding of the course material. As such, referencing your answers is not required unlessyou are taking information from sources other than your textbook/lecture notes/brain. Ifincluding references, they should be specifically formatted as per the Journal of Physiology. A fulllist of instructions can be found here: JoP References Instructions. An example is given blow:In Reference list (note the formatting of the reference):Simpson LL, Busch SA, Oliver SJ, Ainslie PN, Stembridge M, Steinback CD and Moore JP (2019).Baroreflex control of sympathetic vasomotor activity and resting arterial pressure at highaltitude: insight from Lowlanders and Sherpa. J Physiol 597, 2379–2390.The in-text citation would appear as (Simpson et al. 2019). If Simpson were the only author, thein- text citation would appear as (Simpson, 2019).If using a website, you should be able to clearly identify an author for the information provided. Ifno such author can be found, you should question the validity of the information presented. Assuch, you should be conscious of the quality of the references you choose and use texts orjournal articles wherever possible.
1. Starting with the action potential on the sarcolemma, create a flow chart that describesthe events of excitation contraction coupling and the contraction cycle in skeletal muscle.Which of these events is prevented from occurring during rigor mortis and why? (8marks)2. Explain why the corneal reflex can be considered a cranial somatic reflex that is bothipsilateral and contralateral (3 marks)3. For the following hormones, identify their site of production (name the gland, tissue orstructure that produces them), their classification (peptide, steroid or amine) their primarytargets, and their main effects. Which of the hormones listed is/are considered aneurohormone? (5 marks)Hormone Site of production Classification Targets Main EffectCalcitoninGonadotropinReleasingHormone (GnRH)LeptinThyrotropin(TSH)Vasopressin(Anti-diureticHormone)4. A person has a genetic disorder that causes a malfunction in the pendrin transporter inthyroid follicular cells.a) How would synthesis of thyroid hormones be affected and what one word wouldyou use to describe the resulting condition? (2 marks)b) Would you describe the pathology of this condition as a primary or secondary ortertiary pathology? Explain why. (2 marks)c) What specific process involved in thyroid hormone synthesis is affected? (1 mark)5. During the ovarian cycle what feedback mechanism causes the LH surge that results inovulation and which endocrine glands, hormones, and target cells are involved? (4 marks)
